161095-99-4

Basic information

• Product Name: 3,3-bis(phenylthio)-2-piperidone
• Synonyms: 3,3-bis(phenylthio)-2-piperidone
• CAS NO: 161095-99-4
• Molecular Weight: 315.46
• Mol File: 161095-99-4.mol

Chemical Properties

• CAS DataBase Reference: 3,3-bis(phenylthio)-2-piperidone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-bis(phenylthio)-2-piperidone(161095-99-4)
• EPA Substance Registry System: 3,3-bis(phenylthio)-2-piperidone(161095-99-4)

Safety Data

• Hazardous Substances Data: 161095-99-4(Hazardous Substances Data)

Upstream product

• 675-20-7 piperidin-2-one 
• 882-33-7 diphenyldisulfane 
• 3553-93-3 1-(trimethylsilyl)piperidin-2-one 

Downstream Products

• 59953-54-7 3,3-bis(phenylthio)-1-methyl-2-piperidone 
• 161096-00-0 N-benzenesulfonyl-3,3-bis(phenylthio)-2-piperidone 
• 161096-01-1 N-methoxycarbonyl-3,3-bis(phenylthio)-2-piperidone 

Relevant articles and documents

A straightforward synthesis of functionalized cis-perhydroisoquinolin-1-ones

Base-catalyzed annulation reactions of 5,6-dihydro-2(1H)-pyridones with Nazarov-type reagents are reported. The effect of the solvent polarity and the concentration of the reagents is studied. The process involves two successive Michael additions and stereoselectively provides functionalized cis-perhydroisoquinolin-1-ones.

Diels-Alder Reaction of the N-Protected 3-Phenylthio-2(1H)-dihydropyridinone Derivatives

Efficient methods for the preparation of N-protected 3-phenylthio-2(1H)-dihydropyridinones from 2-piperidone and their Diels-Alder reaction with 2-trimethylsilyloxybutadiene are described.The role of the electron-withdrawing N-protecting group in the dienophiles is rationalized in terms of the lowered energy level in LUMO.