1610967-04-8Relevant articles and documents
Bicyclization of isocyanides with alkenoyl bis(ketene dithioacetals): Access to 6,7-dihydro-1 h -indol-4(5 h)-ones
Li, Yifei,Xu, Xianxiu,Shi, Hui,Pan, Ling,Liu, Qun
, p. 5929 - 5933 (2014)
The tandem [3 + 2] cycloaddition/intramolecular imidoyl anion trapping strategy has been successfully applied for the synthesis of 6,7-dihydro-1H- indol-4(5H)-ones from alkenoyl bis(ketene dithioacetals) and tosylmethyl isocyanide. The reaction proceeded smoothly under mild reaction conditions to afford bicyclization products in high to excellent yields in a single step.