161097-77-4 Usage
Uses
Used in Pharmaceutical Industry:
Cimicifugoside H-2 is used as a potential therapeutic agent for its anti-inflammatory properties, which can be beneficial in treating various inflammatory conditions. Its anti-tumor effects also make it a candidate for cancer treatment, particularly in pre-clinical studies where its efficacy and safety are being evaluated.
Used in Women's Health Research:
Due to its estrogenic and anti-estrogenic activities, Cimicifugoside H-2 is used as a subject of research in women's health, specifically for conditions related to hormonal imbalances or hormone-dependent disorders. CIMICIFUGOSIDE H-2's dual activities suggest it may have applications in managing symptoms associated with menopause or other hormone-related health issues.
Used in Hormone-Related Condition Research:
Cimicifugoside H-2 is used as a research compound to explore its potential in treating hormone-related conditions, given its ability to modulate estrogen levels. This makes it a candidate for further investigation into its role in conditions such as polycystic ovary syndrome (PCOS) or other endocrine disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 161097-77-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,0,9 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 161097-77:
(8*1)+(7*6)+(6*1)+(5*0)+(4*9)+(3*7)+(2*7)+(1*7)=134
134 % 10 = 4
So 161097-77-4 is a valid CAS Registry Number.
161097-77-4Relevant academic research and scientific papers
Studies on the Chinese crude drug 'shoma'. IX. Three novel cycloanostanol xylosides, cimicifugosides H-1, H-2 and H-5, from Cimicifuga Rhizome
Koeda,Aoki,Sakurai,Nagai
, p. 771 - 776 (2007/10/02)
Three new cyclolanostanol xylosides were isolated from a batch of commercial Cimicifuga Rhizome, cimicifugoside H-1 (1), C35H52O9, mp 260-262°C, [α](D) -43.5°, cimicifugoside H-2 (2), C35H54O10, mp 227-229°C, [α](D) -38.8°, and cimicifugoside H-5 (3), C35H52O10, mp 262-264°C, [α](D) -22.9°, together with known glycosides, actein and 27-deoxyactein. Their structures were determined on the basis of chemical and spectrometric evidence including an X-ray crystallographic analysis. The structure of cimicifugoside H-1 (1) was established as (20R,24R)-24,25-epoxy-11β-hydroxy-3-β-(β-D-xylopyranosyloxy)-9,19-c yclolanost-7-ene-16,23-dione. Cimicifugoside H-5 (3) is the 15-hydroxylated derivative of 1. Since 1 changed into cimicifugoside H-2 (2) on treatment with p-toluenesulfonic acid, 2 has a 24R,25-diol structure derived from 1 by opening its epoxy ring.