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Cimicifugoside H-2, a triterpene glycoside found in the plant Cimicifuga foetida, also known as Shengma, is a chemical compound that has garnered attention for its potential pharmacological properties. It is recognized for its anti-inflammatory and anti-tumor effects, as well as its estrogenic and anti-estrogenic activities, which make it a promising candidate for research in women's health and hormone-related conditions.

161097-77-4

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161097-77-4 Usage

Uses

Used in Pharmaceutical Industry:
Cimicifugoside H-2 is used as a potential therapeutic agent for its anti-inflammatory properties, which can be beneficial in treating various inflammatory conditions. Its anti-tumor effects also make it a candidate for cancer treatment, particularly in pre-clinical studies where its efficacy and safety are being evaluated.
Used in Women's Health Research:
Due to its estrogenic and anti-estrogenic activities, Cimicifugoside H-2 is used as a subject of research in women's health, specifically for conditions related to hormonal imbalances or hormone-dependent disorders. CIMICIFUGOSIDE H-2's dual activities suggest it may have applications in managing symptoms associated with menopause or other hormone-related health issues.
Used in Hormone-Related Condition Research:
Cimicifugoside H-2 is used as a research compound to explore its potential in treating hormone-related conditions, given its ability to modulate estrogen levels. This makes it a candidate for further investigation into its role in conditions such as polycystic ovary syndrome (PCOS) or other endocrine disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 161097-77-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,0,9 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 161097-77:
(8*1)+(7*6)+(6*1)+(5*0)+(4*9)+(3*7)+(2*7)+(1*7)=134
134 % 10 = 4
So 161097-77-4 is a valid CAS Registry Number.

161097-77-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name CIMICIFUGOSIDE H-2

1.2 Other means of identification

Product number -
Other names cimetex

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:161097-77-4 SDS

161097-77-4Upstream product

161097-77-4Downstream Products

161097-77-4Relevant academic research and scientific papers

Studies on the Chinese crude drug 'shoma'. IX. Three novel cycloanostanol xylosides, cimicifugosides H-1, H-2 and H-5, from Cimicifuga Rhizome

Koeda,Aoki,Sakurai,Nagai

, p. 771 - 776 (2007/10/02)

Three new cyclolanostanol xylosides were isolated from a batch of commercial Cimicifuga Rhizome, cimicifugoside H-1 (1), C35H52O9, mp 260-262°C, [α](D) -43.5°, cimicifugoside H-2 (2), C35H54O10, mp 227-229°C, [α](D) -38.8°, and cimicifugoside H-5 (3), C35H52O10, mp 262-264°C, [α](D) -22.9°, together with known glycosides, actein and 27-deoxyactein. Their structures were determined on the basis of chemical and spectrometric evidence including an X-ray crystallographic analysis. The structure of cimicifugoside H-1 (1) was established as (20R,24R)-24,25-epoxy-11β-hydroxy-3-β-(β-D-xylopyranosyloxy)-9,19-c yclolanost-7-ene-16,23-dione. Cimicifugoside H-5 (3) is the 15-hydroxylated derivative of 1. Since 1 changed into cimicifugoside H-2 (2) on treatment with p-toluenesulfonic acid, 2 has a 24R,25-diol structure derived from 1 by opening its epoxy ring.

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