1610998-23-6Relevant articles and documents
Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties
Spadoni, Gilberto,Bedini, Annalida,Bartolucci, Silvia,Pala, Daniele,Mor, Marco,Riccioni, Teresa,Borsini, Franco,Cabri, Walter,Celona, Diana,Marzi, Mauro,Tarzia, Giorgio,Rivara, Silvia,Minetti, Patrizia
, p. 8 - 35 (2014/05/06)
Many known 5-HT7 ligands contain either a serotonin-like or an arylpiperazine structure that, in published SAR studies, are generally supposed to bind the same receptor pocket. Conversely, we explored the hypothesis that two such moieties can c