161104-50-3Relevant academic research and scientific papers
Asymmetric Synthesis of ent-Corey Lactone Alcohol and its 12-(all-cys)- and 11-Epimers via Free Radical 5-exo-trig-C,C Cyclization
Mulzer, Johann,Kermanchahi, Abdul Kader,Buschmann, Juergen,Luger, Peter
, p. 531 - 540 (2007/10/02)
Asymmetric eight-step syntheses are reported for the ent-Corey lactone alcohol derivatives 3a-d and their epimers 4a-d and 14a, b from (R)-2,3-isopropylidene glyceraldehyde (5) as the starting material.The key step of the synthesis is the free radical cyc
