161105-93-7Relevant academic research and scientific papers
Structure-activity relationships of (E)-5-(2-bromovinyl)uracil and related pyrimidine nucleosides as antiviral agents for herpes viruses
Choi, Yongseok,Li, Ling,Grill, Sue,Gullen, Elizabeth,Lee, Chang Soo,Gumina, Giuseppe,Tsujii, Eisaku,Cheng, Yung-Chi,Chu, Chung K.
, p. 2538 - 2546 (2000)
A series of (E)-5-(2-bromovinyl)uracil analogues and related nucleosides was synthesized, and their antiviral activities were evaluated. (E)-5-(2- Bromovinyl)-2'-deoxy-L-uridine (L-BVDU, 2), 1-(β-L-arabinofuranosyl)-(E)-5- (2-bromovinyl)uracil (L-BVAU, 4)
5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use
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, (2008/06/13)
The present invention relates to pyrimidine nucleoside compounds and their use to treat viral infections of Varicella Zoster virus and Epstein Barr Virus, as well as cancers which are complications of Epstein Barr virus.
