161111-65-5

Basic information

• Product Name: 3-(4-HYDROXY-PHENYL)-INDENO[1,2-C]PYRIDAZIN-5-ONE
• Synonyms: 3-(4-HYDROXY-PHENYL)-INDENO[1,2-C]PYRIDAZIN-5-ONE;3-(4-HYDROXYPHENYL)-5H-INDENO[1,2-C]PYRIDAZIN-5-ONE
• CAS NO: 161111-65-5
• Molecular Formula: C17H10N2O2
• Molecular Weight: 274.27
• Mol File: 161111-65-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-HYDROXY-PHENYL)-INDENO[1,2-C]PYRIDAZIN-5-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-HYDROXY-PHENYL)-INDENO[1,2-C]PYRIDAZIN-5-ONE(161111-65-5)
• EPA Substance Registry System: 3-(4-HYDROXY-PHENYL)-INDENO[1,2-C]PYRIDAZIN-5-ONE(161111-65-5)

Safety Data

• Hazardous Substances Data: 161111-65-5(Hazardous Substances Data)

Upstream product

• 99-93-4 4-Hydroxyacetophenone 
• 485-47-2 indan-1,2,3-trione hydrate 

Relevant articles and documents

Synthesis, benzodiazepine receptor affinity and anticonvulsant activity of 5-H-indeno[1,2-c]pyridazine derivatives

Title compounds 1-36 were synthesized by reacting hydrazine with aldol adducts obtained from ninhydrin and methyl or α methylene ketones and aldehydes. Some of them showed a low, but significant benzodiazepine receptor affinity whose variation was interpreted through a structure-activity relationships study based on qualitative correlations and Comparative Molecular Field Analysis (CoMFA). Some indeno-pyridazine derivatives were found to possess an interesting anticonvulsant activity which however does not seem simply related to the benzodiazepine receptor modulation.