16112-40-6Relevant academic research and scientific papers
B(C6F5)3-catalyzed dehydrogenative cyclization of: N -tosylhydrazones and anilines via a Lewis adduct: A combined experimental and computational investigation
Guru, Murali Mohan,De, Sriman,Dutta, Sayan,Koley, Debasis,Maji, Biplab
, p. 7964 - 7974 (2019/09/06)
Tris(pentafluorophenyl)borane-catalyzed dehydrogenative-cyclization of N-tosylhydrazones with aromatic amines has been disclosed. This metal-free catalytic protocol is compatible with a range of functional groups to provide both symmetrical and unsymmetrical 3,4,5-triaryl-1,2,4-triazoles. Mechanistic experiments and density functional theory (DFT) studies suggest an initial Lewis adduct formation of N-tosylhydrazone with B(C6F5)3 followed by sequential intermolecular amination of the borane adduct with aniline, intramolecular cyclization and frustrated Lewis pair (FLP)-catalyzed dehydrogenation for the generation of substituted 1,2,4-triazoles.
A novel synthesis of 3,4,5-triaryl-1,2,4-4H-triazoles from 2,5-diaryl-1,3,4-oxadiazoles and aluminium anilides
Chiriac, Constantin I.,Tanasa, Fulga,Nechifor, Marioara
experimental part, p. 175 - 177 (2011/08/03)
3,4,5-Triaryl-1,2,4-4H-triazoles have been prepared in 70-91% yields by a simple and easy to control one-pot procedure from 2,5- diaryl-1,3,4-oxadiazoles and aluminium anilides.
