1611489-22-5Relevant academic research and scientific papers
Synthesis of benzimidazo[2,1-b]benzothiazole derivatives through sequential Cu-catalyzed domino coupling and Pd-catalyzed Suzuki reaction
Gao, Jilong,Zhu, Jiaoyan,Chen, Lubin,Shao, Yingying,Zhu, Jiaqi,Huang, Yijia,Wang, Xiaoxia,Lv, Xin
, p. 3367 - 3373 (2014/06/09)
A variety of benzo[d]benzo[4,5]imidazo[2,1-b]thiazoles were efficiently and conveniently synthesized from the Cu-catalyzed domino coupling of o-dihaloarenes with 2-mercaptobenzimidazoles. The reaction is also applicable to a series of multi-functional substrates, affording the halo-containing products with excellent selectivity. The brominated products can further react with arylboronic acids under Pd catalysis to furnish the aryl-substituted benzimidazo[2,1-b]benzothiazole derivatives.
