161154-16-1 Usage
General Description
7-Chlorotetrazolo[1,5-a]quinoxalin-4(5H)-one is a chemical compound with the molecular formula C8H4ClN5O. It is a heterocyclic compound that contains a tetrazole ring fused to a quinoxaline ring. 7-Chlorotetrazolo[1,5-a]quinoxalin-4(5H)-one is a potential pharmacological agent with various biological activities, including antimicrobial and antitumor properties. It has been studied for its potential use in the development of novel therapeutic agents. Additionally, 7-Chlorotetrazolo[1,5-a]quinoxalin-4(5H)-one has shown potential as a synthetic intermediate in organic chemistry and pharmaceutical research. Further research and development of this compound may lead to the discovery of new drugs and therapeutic agents with important medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 161154-16-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,1,5 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 161154-16:
(8*1)+(7*6)+(6*1)+(5*1)+(4*5)+(3*4)+(2*1)+(1*6)=101
101 % 10 = 1
So 161154-16-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H4ClN5O/c9-4-1-2-6-5(3-4)10-8(15)7-11-12-13-14(6)7/h1-3H,(H,10,15)
161154-16-1Relevant articles and documents
A Synthetic Route Toward Tetrazoles: The Thermolysis of Geminal Diazides
Holzschneider, Kristina,Kirsch, Stefan F.,Mohr, Fabian,Tong, My Linh
, (2019)
A new synthetic route toward the tetrazole core is described, which is based on a general fragmentation pattern that was found in a range of compounds featuring geminal diazido units. Through a simple two-step procedure, the synthesis of structurally diverse target compounds containing a tetrazole, such as tetrazoloquinoxalinones, benzoylaryltetrazoles, tetrazolotriazinones, and tetrazoloazepinones, was easily accomplished, starting from broadly accessible substrates (i.e., oxindoles, diarylethanones, pyrazolones, and phenanthrols). The initial oxidative diazidation reaction with iodine and sodium azide under mild conditions is followed by the thermal fragmentation under microwave irradiation, leading to the tetrazole products. Noteworthy, an experimental solution is presented in which the potentially hazardous diazide intermediates are not isolated and the concentration of crude reaction mixtures containing diazides is not required to achieve the tetrazoles in good yields.
