161156-00-9

Basic information

• Product Name: METHYL 4,6,7-TRIMETHOXYINDOLE-2-CARBOXYLATE
• Synonyms: METHYL 4,6,7-TRIMETHOXYINDOLE-2-CARBOXYLATE
• CAS NO: 161156-00-9
• Molecular Formula: C13H15NO5
• Molecular Weight: 265.2619
• Mol File: 161156-00-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 435.7±40.0 °C(Predicted)
• Appearance: /
• Density: 1.252±0.06 g/cm3(Predicted)
• PKA: 14.91±0.30(Predicted)
• CAS DataBase Reference: METHYL 4,6,7-TRIMETHOXYINDOLE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4,6,7-TRIMETHOXYINDOLE-2-CARBOXYLATE(161156-00-9)
• EPA Substance Registry System: METHYL 4,6,7-TRIMETHOXYINDOLE-2-CARBOXYLATE(161156-00-9)

Safety Data

• Hazardous Substances Data: 161156-00-9(Hazardous Substances Data)

Downstream Products

• 161156-01-0 4,6,7-Trimethoxyindole-2-carboxylic acid 

Relevant articles and documents

Preparation method of methoxy-substituted methyl-1H-indole-2-carboxylate

The invention relates to the technical field of organic synthesis, and provides a preparation method of methoxy-substituted methyl-1H-indole-2-carboxylate. The preparation method comprises the following steps: mixing methoxy-substituted methyl(Z)-2-azido-3-phenyl acrylate, a ruthenium catalyst and tetrahydrofuran, and carrying out a cyclization reaction to obtain the methoxy-substituted methyl-1H-indole-2-carboxylate. According to the preparation method provided by the invention, the ruthenium catalyst is adopted for catalysis, and the methoxy-substituted methyl-1H-indole-2-carboxylate can beprepared without using high-toxicity toluene and high-toxicity xylene as solvents. The preparation method provided by the invention is relatively low in toxicity and relatively high in safety coefficient; and the yield of a product, namely the methoxy-substituted methyl-1H-indole-2-carboxylate purified by the method provided by the invention is relatively high and is 93% or above.