161183-22-8 Usage
Description
(3R,4S)-1-tert-Butoxycarbonyl-3-acetoxy-4-phenyl-2-azetidinone is a white solid chemical compound with the molecular formula C15H19NO4. It is a derivative of 2-azetidinone, featuring a four-membered lactam ring, and is commonly used as a reagent in organic synthesis. (3R,4S)-1-tert-Butoxycarbonyl-3-acetoxy-4-phenyl-2-azetidinone is known for its versatility as a building block in the synthesis of various pharmaceutical compounds and its ability to act as a chiral auxiliary in asymmetric synthesis reactions. The presence of the tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom provides stability to the molecule during synthetic processes, making it a valuable component in medicinal chemistry and pharmaceutical development.
Uses
Used in Pharmaceutical Synthesis:
(3R,4S)-1-tert-Butoxycarbonyl-3-acetoxy-4-phenyl-2-azetidinone is used as a building block for the synthesis of various pharmaceutical compounds due to its structural features and reactivity. Its chiral nature allows for the creation of enantiomerically pure products, which is crucial for the development of effective and safe medications.
Used in Asymmetric Synthesis:
In the field of asymmetric synthesis, (3R,4S)-1-tert-Butoxycarbonyl-3-acetoxy-4-phenyl-2-azetidinone is used as a chiral auxiliary to induce selectivity in chemical reactions. This application is vital for producing enantiomerically enriched compounds, which are essential in many biologically active molecules and pharmaceuticals.
Used in Organic Synthesis as a Reagent:
(3R,4S)-1-tert-Butoxycarbonyl-3-acetoxy-4-phenyl-2-azetidinone serves as a versatile reagent in organic synthesis, where its unique structure and functional groups can be utilized in various reaction types, such as nucleophilic additions, cycloadditions, and rearrangements, to construct complex organic molecules.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, (3R,4S)-1-tert-Butoxycarbonyl-3-acetoxy-4-phenyl-2-azetidinone is used as a key intermediate in the development of new drugs and therapeutic agents. Its ability to be modified and functionalized makes it a valuable tool for exploring novel chemical space and discovering potential drug candidates.
Used in the Development of Drug Delivery Systems:
(3R,4S)-1-tert-Butoxycarbonyl-3-acetoxy-4-phenyl-2-azetidinone can be incorporated into drug delivery systems to improve the pharmacokinetics and biodistribution of therapeutic agents. Its chemical properties may allow for the design of prodrugs or drug conjugates that can be activated or released under specific conditions within the body, enhancing the efficacy and safety of treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 161183-22-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,1,8 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 161183-22:
(8*1)+(7*6)+(6*1)+(5*1)+(4*8)+(3*3)+(2*2)+(1*2)=108
108 % 10 = 8
So 161183-22-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H19NO5/c1-10(18)21-13-12(11-8-6-5-7-9-11)17(14(13)19)15(20)22-16(2,3)4/h5-9,12-13H,1-4H3/t12-,13+/m0/s1