161199-05-9Relevant academic research and scientific papers
An efficient methodology to substituted furans via oxidation of functionalized α-diazo-β-ketoacetates
Truong, Phong,Xu, Xinfang,Doyle, Michael P.
scheme or table, p. 2093 - 2096 (2011/05/09)
DMDO oxidation of functionalized α-diazo-β-ketoacetates, formed by zinc triflate catalyzed Mukaiyama-aldol condensation of methyl diazoacetoacetate with aldehydes, occurred in quantitative yield to form dihydrofuranols that undergo acid catalyzed dehydrat
The Chemistry of Vicinal Tricarbonyls. A New Synthesis of Substituted Furans.
Wasserman, Harry H.,Lee, Gary M.
, p. 9783 - 9786 (2007/10/02)
Enolates of acyl phosphoranylidene carboxylates react with aldehydes to form secondary alcohols which undergo intramolecular addition to the central carbonyl of a vicinal tricarbonyl unit, generated in a separate step.The resulting dihydrofuranols undergo acid-catalyzed dehydration to form 3-hydroxyfuran-2-carboxylates.
