1612184-15-2

Upstream product

• 183158-34-1 2,3-dimethylphenylboronic acid 
• 1612184-09-4 4-chloro-6-(2,3-dimethylphenyl)pyrimidin-2-amine 
• 1612182-22-5 tert-butyl N-(2-{[2-amino-6-(2,3-dimethylphenyl)pyrimidin-4-yl]amino}ethyl)-carbamate 
• 1440426-67-4 tert-butyl N-[2-[(2-amino-6-chloro-pyrimidin-4-yl)amino]ethyl]carbamate 

Downstream Products

• 1612183-91-1 4-N-{2-[(6-chloropyridazin-3-yl)amino]ethyl}-6-(2,3-dimethylphenyl)pyrimidine-2,4-diamine 
• 1612183-52-4 N-(2-{[2-amino-6-(2,3-dimethylphenyl)pyrimidin-4-yl]amino}ethyl)-4-methanesulfonylbenzene-1-sulfonamide 

Relevant academic research and scientific papers

MTH1 INHIBITORS FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE CONDITIONS

A compound of formula (I), or a pharmaceutically acceptable salt thereof, for use in the treatment of autoimmune diseases and inflammatory conditions.

MTH1 INHIBITORS FOR TREATMENT OF CANCER

A compound of formula I, (I) or a pharmaceutically-acceptable salt thereof. The compound is useful in the treatment of cancer.