1612240-19-3

Basic information

• Product Name: 5-(benzyloxy)-2-chlorobicyclo[4.2.0]octa-1,3,5-trien-7-ol
• Synonyms: 5-(benzyloxy)-2-chlorobicyclo[4.2.0]octa-1,3,5-trien-7-ol
• CAS NO: 1612240-19-3
• Molecular Weight: 260.72
• Mol File: 1612240-19-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(benzyloxy)-2-chlorobicyclo[4.2.0]octa-1,3,5-trien-7-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzyloxy)-2-chlorobicyclo[4.2.0]octa-1,3,5-trien-7-ol(1612240-19-3)
• EPA Substance Registry System: 5-(benzyloxy)-2-chlorobicyclo[4.2.0]octa-1,3,5-trien-7-ol(1612240-19-3)

Safety Data

• Hazardous Substances Data: 1612240-19-3(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 13659-24-0 3-bromo-4-chlorophenol 
• 675825-21-5 Lithium enolate of the acetaldehyde 

Downstream Products

• 1612240-24-0 5-(benzyloxy)-2-chlorobicyclo[4.2.0]octa-1,3,5-trien-7-one 

Relevant articles and documents

Enantioselective Rh-Catalyzed Carboacylation of C=N Bonds via C-C Activation of Benzocyclobutenones

Herein we describe the first enantioselective Rh-catalyzed carboacylation of oximes (imines) via C-C activation. In this transformation, the benzocyclobutenone C1-C2 bond is selectively activated by a low valent rhodium catalyst and subsequently the resulting two Rh-C bonds add across a C=N bond, which provides a unique approach to access chiral lactams. A range of polycyclic nitrogen-containing scaffolds were obtained in good yields with excellent enantioselectivity. Further derivatization of the lactam products led to a rapid entry to various novel fused heterocycles.