161227-65-2Relevant academic research and scientific papers
An Unusual Dependence of Counterion During Wittig Methylenation of Bis-Heteroaryl Ketones
Subramanyam, Chakrapani
, p. 9249 - 9252 (1995)
Attempted Wittig methylenation of some bis-heteroaromatic ketones (8, 11 and 13) using MeP+Ph3Br- and n-BuLi gave none of the desired olefin.However, when KtBuO was used as the base for generation of the ylide, efficient olefination of these ketones was observed.A possible mechanistic pathway for this interesting but unprecedented observation is proposed.
Discovery of 6,11-ethano-12,12-diaryl-6,11-dihydrobenzo[b]quinolizinium cations, a novel class of N-methyl-D-aspartate antagonists
Subramanyam,Mallamo,Dority Jr.,Earley,Kumar,Aimone,Ault,Miller,Luttinger,DeHaven-Hudkins
, p. 21 - 27 (2007/10/02)
6,11-Ethano-12,12-diaryl-6,11-dihydrobenzo[b]quinolizinium cations 8, a novel class of N-methyl-D-aspartate (NMDA) antagonists acting at the phencyclidine site, have been identified. Structure-activity relationship studies around the lead compound 8a led
