161233-97-2

Basic information

• Product Name: 2-CYANO-4-PYRIDINE CARBOXYLIC ACID
• Synonyms: 2-CYANOPYRIDINE-4-CARBOXYLIC ACID;2-CYANO-4-PYRIDINE CARBOXYLIC ACID;2-CYANOISONICOTINIC ACID;4-Pyridinecarboxylicacid,2-cyano-(9CI);-Cyano-4-pyridinecarboxylicacid;4-Pyridinecarboxylicacid, 2-cyano-
• CAS NO: 161233-97-2
• Molecular Formula: C7H4N2O2
• Molecular Weight: 148.12
• Product Categories: CARBOXYLICACID;NITRILE;PYRIDINE;Pyridine series;Pyridines
• Mol File: 161233-97-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 335 °C
• Boiling Point: 478.4 °C at 760 mmHg
• Flash Point: 243.1 °C
• Appearance: /
• Density: 1.42 g/cm³
• Vapor Pressure: 5.83E-10mmHg at 25°C
• Refractive Index: 1.596
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 2.81±0.10(Predicted)
• CAS DataBase Reference: 2-CYANO-4-PYRIDINE CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANO-4-PYRIDINE CARBOXYLIC ACID(161233-97-2)
• EPA Substance Registry System: 2-CYANO-4-PYRIDINE CARBOXYLIC ACID(161233-97-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 161233-97-2(Hazardous Substances Data)

Usage

Chemical Properties

off-white solid

InChI:InChI=1/C7H4N2O2/c8-4-6-3-5(7(10)11)1-2-9-6/h1-3H,(H,10,11)

Upstream product

• 773837-37-9 sodium cyanide 
• 13602-12-5 Isonicotinic acid N-oxide 
• 55-22-1 pyridine-4-carboxylic acid 
• 94413-64-6 2-Cyano-4-carbomethoxypyridine 
• 3783-38-8 methyl isonicotinate N-oxide 
• 66572-56-3 2-bromoisonicotinic acid 

Downstream Products

• 131747-70-1 2-Cyano-4-pyridinecarboxaldehyde 
• 71935-32-5 2-Cyano-4-(hydroxymethyl)pyridine 
• 863014-10-2 2-aminomethylisonicotinic acid 
• 135048-32-7 2-cyanoisonicotinic acid hydrazide 

Relevant articles and documents

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The invention provides a method for converting halogenopyridinecarboxylic acid into cyanopyridinecarboxylic acid. The method is characterized in that the halogenopyridinecarboxylic acid reacts with acyanidation reagent to form the cyanopyridinecarboxylic acid. The preparation method makes the halogenopyridinecarboxylic acid directly converted into the cyanopyridinecarboxylic acid in one step, sothe method has the advantages of omission of esterification and hydrolysis steps, simplification of synthesis steps, shortening of the reaction process, manpower saving, productivity increase, reduction of three wastes, suitableness for industrial production, and broad application prospect.

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