161257-64-3

Basic information

• Product Name: L-Proline, 5-(cyanomethyl)-, ethyl ester, trans- (9CI)
• Synonyms: L-Proline, 5-(cyanomethyl)-, ethyl ester, trans- (9CI)
• CAS NO: 161257-64-3
• Molecular Formula: C9H14N2O2
• Molecular Weight: 182.21966
• Product Categories: PYRROLE
• Mol File: 161257-64-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Proline, 5-(cyanomethyl)-, ethyl ester, trans- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Proline, 5-(cyanomethyl)-, ethyl ester, trans- (9CI)(161257-64-3)
• EPA Substance Registry System: L-Proline, 5-(cyanomethyl)-, ethyl ester, trans- (9CI)(161257-64-3)

Safety Data

• Hazardous Substances Data: 161257-64-3(Hazardous Substances Data)

Upstream product

• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 2537-48-6 diethyl 1-cyanomethylphosphonate 
• 194594-23-5 5-hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 

Relevant articles and documents

Diastereoselective functionalization of 5-hydroxy prolinates by tandem Horner-Emmons-Michael reaction

The tandem Horner-Emmons-Michael reaction of the hemiaminal derived from N-BOC protected pyroglutamic esters with stabilised phosphonates gives 5-substituted prolinates in high diastereomeric and enantiomeric excess through 1,4-asymmetric induction process.