161262-84-6Relevant articles and documents
Formation of Pyrrole Derivatives from Heteroatom-Substituted Acetonitriles
Jeng, Huey-Jiuan,Fang, Jim-Min
, p. 803 - 812 (2007/10/03)
Aminomalonitrile reacted with conjugated carbonyl compounds to give 3H-pyrrolines.Treatment of 2-chloro-2-phenylthioacetonitrile with alkenes in the presence of potassium t-butoxide afforded 1-phenylthiocyclopropanecarbonitriles, which reacted with nucleophiles in 1,2-, 1,4- or 1,6-addition modes.The 1,2-adducts (cyclopropylimines) rearranged in situ to give substituted pyrolles. - Keywords: Aminomalononitrile; 2-Chloro-2-phenylthioacetonitrile; 1-Phenylthiocyclopropanecarbonitrile; 3H-Pyrroline; Pyrrole.