161275-76-9

Upstream product

• 123457-16-9 (5S)-5-(3-p-nitrobenzyloxycarbonyl-2-oxopropyl)pyrrolidin-2-one 
• 161157-89-7 (5S)-<(4S)-(4-ethyl-1,3-thiazolidine-2-thion-3-yl)carbonylmethyl>pyrrolidin-2-one 
• 123457-17-0 (5S)-5-(3-diazo-3-p-nitrobenzyloxycarbonyl-2-oxopropyl)pyrrolidin-2-one 

Downstream Products

• 126149-96-0 (5S)-2-p-nitrobenzyloxycarbonyl-3-((1-p-nitrobenzyloxycarbonyl)azetidin-3-yl)thio-8-oxo-1-azabicyclo<3.3.0>oct-2-ene 
• 126660-27-3 (5S)-2-p-nitrobenzyloxycarbonyl-3-(2-p-nitrobenzyloxycarbonylamino)ethylthio-8-oxo-1-azabicyclo<3.3.0>oct-2-ene 
• 161157-90-0 (5S)-3-diphenylphosphoryloxy-2-p-nitrobenzyloxycarbonyl-8-oxo-1-azabicyclo<3.3.0>oct-2-ene 

Relevant academic research and scientific papers

Preliminary Experiments for Asymmetric Total Synthesis of the Thienamycin-Like γ-Lactam

Optically active bicycle γ-lactam carboxylates (3 and 4) were readily synthesized by employing chiral 5-alkylated pyrrolidin-2-one (9b) obtained from an asymmetric alkylation with tin(II) enolate (6a) onto 5-acetoxypyrrolidin-2-one (7b).