1612786-53-4Relevant academic research and scientific papers
NIS-assisted aza-Friedel-Crafts reaction with α-carbamoysulfides as precursors of N-carbamoylimines
George, Nicolas,Bekkaye, Mathieu,Alix, Aurelien,Zhu, Jieping,Masson, Geraldine
supporting information, p. 3621 - 3625 (2014/04/03)
A general and practical N-iodosuccinimide (NIS)-promoted aza-Friedel-Crafts reaction of various aromatic nucleophiles with N-acylimines generated in situ from α-amidosulfides to give a rapid access to highly functionalized amines is described. The newly developed methodology is very mild, fast, efficient, and complementary.
