1612839-99-2

Basic information

• Product Name: lup-20(29)-ene-3β,16β-diol di-p-bromobenzoate
• Synonyms: lup-20(29)-ene-3β,16β-diol di-p-bromobenzoate
• CAS NO: 1612839-99-2
• Molecular Weight: 808.734
• Mol File: 1612839-99-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: lup-20(29)-ene-3β,16β-diol di-p-bromobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: lup-20(29)-ene-3β,16β-diol di-p-bromobenzoate(1612839-99-2)
• EPA Substance Registry System: lup-20(29)-ene-3β,16β-diol di-p-bromobenzoate(1612839-99-2)

Safety Data

• Hazardous Substances Data: 1612839-99-2(Hazardous Substances Data)

Upstream product

• 10070-48-1 calenduladiol 
• 586-75-4 4-chlorobenzoyl chloride 

Relevant articles and documents

Preparation, anticholinesterase activity and molecular docking of new lupane derivatives

A set of twenty one lupane derivatives (2-22) was prepared from the natural triterpenoid calenduladiol (1) by transformations on the hydroxyl groups at C-3 and C-16, and also on the isopropenyl moiety. The derivatives were tested for their inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) and some structure-activity relationships were outlined with the aid of enzyme kinetic studies and docking modelization. The most active compound resulted to be 3,16,30-trioxolup-20(29)-ene (22), with an IC50 value of 21.5 μM for butyrylcholinesterase, which revealed a selective inhibitor profile towards this enzyme.