161285-07-0Relevant academic research and scientific papers
Design and synthesis of potent and highly selective thrombin inhibitors
Hilpert,Ackermann,Banner,Gast,Gubernator,Hadvary,Labler,Muller,Schmid,Tschopp,Van de Waterbeemd
, p. 3889 - 3901 (2007/10/02)
Thrombin, a serine protease, plays a central role in the initiation and propagation of thrombotic events. An extensive search for new thrombin inhibitors was performed, using an unconventional approach. Screening of small basic molecules for binding in th
