1612872-73-7

Basic information

• Product Name: N-(1-acetyl-5-bromoindolin-7-yl)-4-methylbenzenesulfonamide
• Synonyms: N-(1-acetyl-5-bromoindolin-7-yl)-4-methylbenzenesulfonamide
• CAS NO: 1612872-73-7
• Molecular Weight: 409.304
• Mol File: 1612872-73-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(1-acetyl-5-bromoindolin-7-yl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-acetyl-5-bromoindolin-7-yl)-4-methylbenzenesulfonamide(1612872-73-7)
• EPA Substance Registry System: N-(1-acetyl-5-bromoindolin-7-yl)-4-methylbenzenesulfonamide(1612872-73-7)

Safety Data

• Hazardous Substances Data: 1612872-73-7(Hazardous Substances Data)

Upstream product

• 22190-33-6 5-bromoindoline 
• 22190-38-1 5-bromo-N-acetylindoline 
• 70-55-3 toluene-4-sulfonamide 
• 941-55-9 4-toluenesulfonyl azide 

Relevant articles and documents

Rhodium(III)-catalyzed direct C-7 sulfonamidation and amination of indolines with arylsulfonamides and trifluoroacetamide

A rhodium-catalyzed direct C–H sulfonamidation and amidation of C-7 position of indolines by simple and commercially available arylsulfonamides and trifluoroacetamide has been developed, affording a series of N-arylsulfonamides and N-aryltrifluoroacetamides in moderate to excellent yields, respectively. Notably, this catalytic system is highly convenient on mmol scale.

Ruthenium-catalyzed C7 amidation of indoline C-H bonds with sulfonyl azides

A ruthenium-catalyzed direct C7 amidation of indoline C-H bonds with sulfonyl azides was developed. This procedure allows the synthesis of a variety of 7-amino-substituted indolines, which are useful in pharmaceutical. The good functional tolerances, as well as the mild conditions, are prominent feature of this method.