1613022-98-2

Upstream product

• 77287-34-4 formamide 
• 1993-03-9 o-fluorophenylboronic acid 
• 4928-88-5 methyl 1H-1,2,4-triazole-3-carboxylate 

Downstream Products

• 1245648-20-7 1-(2-fluoro-phenyl)-1H-[1,2,4]-triazole-3-carboxylic acid 
• 1613021-34-3 1-(2-fluorophenyl)-N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-1,2,4-triazole-3-carboxamide trifluoroacetate 
• 1613021-33-2 C₁₉H₁₇FN₈O 

Relevant academic research and scientific papers

Facile One-Pot Synthesis of Methyl 1-Aryl-1H-1,2,4-triazole-3-carboxylates from Nitrilimines with Vilsmeier Reagent

Two convenient and effective one-pot methods have been developed to synthesize methyl 1-aryl-1H-1,2,4-triazole1–3-carboxylates by using hydrazonoyl hydrochlorides (nitrilimines) with Vilsmeier reagent. The first, a direct one-pot method, involved the reac

CXCR7 ANTAGONISTS

Compounds having formula I, or pharmaceutically acceptable salts, hydrates or N-oxides thereof are provided and are useful for binding to CXCR7, and treating diseases that are dependent, at least in part, on CXCR7 activity. Accordingly, the present invention provides in further aspects, compositions containing one or more of the above-noted compounds in admixture with a pharmaceutically acceptable excipient.