1613030-98-0Relevant articles and documents
Polishing wusu acidifies ornament and its preparation method and application
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Paragraph 0064; 0065, (2017/01/23)
The invention discloses chemically modified ursolic acid and its preparation method and use. The chemically modified ursolic acid has a structural formula shown in the following formula, and in the formula, R1 represents acyloxy and R2 represents an amino group. The preparation method comprises the following steps that ursolic acid and acid anhydride undergo a reaction under the catalyst condition to produce 3 beta-acyloxy-ursane-12-ene-28-carboxylic acid compounds 2-5, the compounds 2-5 are acylated by oxalyl chloride under the ice bath condition to form 3-acetoxy-ursane-12-ene-28-acyl chloride, and the 3-acetoxy-ursane-12-ene-28-acyl chloride and aniline undergo a reaction under the acid binding agent condition to produce N-(3 beta-acyloxy-ursane-12-ene-28-acyl)-amine compound. The N-(3 beta-acyloxy-ursane-12-ene-28-acyl)-amine compound has enzymatic activity inhibition effects, can be used in drugs, drinks, foods and health products for preventing, controlling or treating high-blood sugar level diabetes or obesity and belongs to the technical field of drug synthesis.
