16131-74-1

Basic information

• Product Name: 2-(4-methyl-1,3-thiazol-2-yl)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
• CAS NO: 16131-74-1
• Molecular Formula: C₁₂H₁₂N₂O₃S
• Molecular Weight: 264.3003
• Mol File: 16131-74-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 441.7°C at 760 mmHg
• Flash Point: 220.9°C
• Density: 1.487g/cm³
• Vapor Pressure: 5.33E-08mmHg at 25°C
• Refractive Index: 1.641
• CAS DataBase Reference: 2-(4-methyl-1,3-thiazol-2-yl)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methyl-1,3-thiazol-2-yl)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione(16131-74-1)
• EPA Substance Registry System: 2-(4-methyl-1,3-thiazol-2-yl)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione(16131-74-1)

Safety Data

• Hazardous Substances Data: 16131-74-1(Hazardous Substances Data)

Usage

General Description

2-(4-methyl-1,3-thiazol-2-yl)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione, also known as SNS-314, is a synthetic chemical compound with potential anticancer properties. It belongs to the class of thiazole compounds and is a potent and selective inhibitor of Aurora kinase, a key enzyme involved in cell division and growth. SNS-314 has shown promise in preclinical studies as an anti-tumor agent, particularly in the treatment of solid tumors and hematologic malignancies. Its mechanism of action involves the disruption of normal cell division processes, leading to the inhibition of tumor growth. Clinical trials are currently underway to evaluate the safety and efficacy of SNS-314 as a potential treatment for various types of cancer.