1613144-99-2

Upstream product

• 1613144-82-3 {(2R,4S,6S)-4-[(tert-butyldiphenylsilyl)oxy]-6-(2-oxoethyl)-tetrahydro-2H-pyran-2-yl}methyl 4-methylbenzenesulfonate 
• 118629-75-7 (S)-2-hydroxypent-4-en-1-yl 4-methylbenzenesulfonate 
• 1613144-89-0 {(2S,4S,6S)-4-[(tert-butyldiphenylsilyl)oxy]-6-[((2S,4S,6R)-4-hydroxy-6-(tosyloxymethyl)tetrahydro-2H-pyran-2-yl)methyl]tetrahydro-2H-pyran-2-yl}methyl 4-methylbenzenesulfonate 
• 501365-06-6 (R)-2-hydroxypent-4-en-1-yl 4-methylbenzenesulfonate 

Downstream Products

• 1613145-04-2 tert-butyl {(2R,4S,6R)-2-[((2S,4S,6S)-4-(tert-butyldiphenylsilyl)oxy-6-(iodomethyl)tetrahydro-2Hpyran-2-yl)methyl]-6-(iodomethyl)tetrahydro-2H-pyran-4-yl} carbonate 
• 1613145-20-2 (4S,6S)-4-{[(4R,6S)-6-((R)-2-(tert-butyldiphenylsilyloxy)pent-4-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl]methyl}-6-(iodomethyl)-1,3-dioxan-2-one 
• 1613145-21-3 (4S,6R)-4-{[(4R,6S)-6-((R)-2-(tert-butyldiphenylsilyloxy)pent-4-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl]methyl}-6-(iodomethyl)-1,3-dioxan-2-one 
• 1613145-19-9 tert-butyl {(R)-1-[(4R,6S)-6-((R)-2-(tert-butyldiphenylsilyloxy)pent-4-en-1-yl)-2,2-dimethyl-1,3-dioxan-4-yl]pent-4-en-2-yl} carbonate 
• 1613145-16-6 tert-butyl [(4R,6R,8S,10R)-10-(tert-butyldiphenylsilyl)oxy-6,8-dihydroxytrideca-1,12-dien-4-yl]carbonate 
• 1613145-11-1 (4R,6S,8S,10R)-10-[(tert-butyldiphenylsilyl)oxy]trideca-1,12-diene-4,6,8-triol 

Relevant academic research and scientific papers

Total Synthesis of (+)-Cryptocaryol A Using a Prins Cyclization/Reductive Cleavage Sequence

The total synthesis of (+)-cryptocaryol A was achieved in 20 steps from (R)-glycidol. The key steps were a Prins cyclization/reductive cleavage sequence to construct the C5-C11 polyol fragment, a diastereoselective aldol reaction to control the stereogeni

Diastereo- and enantioselective synthesis of 1,3,5,7-tetraol structural units using a Prins cyclisation-reductive cleavage sequence

Stereocontrolled and efficient access to all the diastereomers of 1,3,5,7-tetraol structural units was developed using a Prins cyclisation-reductive cleavage sequence applied to tetrahydropyran aldehydes. Furthermore, these tetraols can be selectively functionalized. This journal is the Partner Organisations 2014.