161315-67-9Relevant academic research and scientific papers
Chemoselective ligation applied to the synthesis of a biantennary N-linked glycoform of CD52
Pratt, Matthew R.,Bertozzi, Carolyn R.
, p. 6149 - 6159 (2007/10/03)
We report here a strategy for the synthesis of N-linked glycopeptide analogues that replace the glycosidic linkages extending from the core pentasaccharide with thioethers amenable to construction by chemoselective ligation. The key building block, a pent
Synthesis of a core trisaccharide as a versatile building block for N-glycans and glycoconjugates
Unverzagt, Carlo
, p. 1369 - 1376 (2007/10/03)
N-Linked oligosaccharides from glycoproteins (N-glycans) can be conveniently assembled with a building block approach. A protected form of the core trisaccharide (β-mannosyl chitobiose) was identified as a key building block. The chitobiose part of the co
A new strategy for the synthesis of the core trisaccharide of asparagine-linked sugar chains
Matsuo, Ichiro,Isomura, Megumi,Walton, Richard,Ajisaka, Katsumi
, p. 8795 - 8798 (2007/10/03)
The core trisaccharide common to all asparagine-linked glycoprotein olisosaccharides was synthesized using two novel processes: 1) regioselective acetylation using lipase, and 2) inversion of the C-2 hydroxyl group of the glucose residue in a glucosyl chi
