1613157-39-3Relevant academic research and scientific papers
Catalytic asymmetric aminolactonization of 1,2-disubstituted alkenoic acid esters: Efficient construction of aminolactones with an all-carbon quaternary stereo-centre
Hajra, Saumen,Akhtar, Sk Md Samim,Aziz, Sk Mohammad
supporting information, p. 6913 - 6916 (2014/06/23)
Chiral BOX-Cu(OTf)2 catalyzed enantioselective aminolactonization of the tert-butyl ester of alkenoic acids has been developed via in situ aziridination using PhINNs as the nitrene source. It provides exclusively trans-γ- and δ-amino lactones including an additional all-carbon quaternary stereo-centre with up to 98% ee in good to excellent yields. the Partner Organisations 2014.
