1613190-53-6

Basic information

• Product Name: 2-(2-(pent-2-ynyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1-phenylethanone
• Synonyms: 2-(2-(pent-2-ynyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1-phenylethanone
• CAS NO: 1613190-53-6
• Molecular Weight: 356.467
• Mol File: 1613190-53-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-(pent-2-ynyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1-phenylethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(pent-2-ynyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1-phenylethanone(1613190-53-6)
• EPA Substance Registry System: 2-(2-(pent-2-ynyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1-phenylethanone(1613190-53-6)

Safety Data

• Hazardous Substances Data: 1613190-53-6(Hazardous Substances Data)

Upstream product

• 61-54-1 tryptamine 
• 3623-15-2 phenyl propargyl ketone 
• 1613190-60-5 C₁₉H₁₈N₂O 
• 81159-43-5 methanesulfonic acid pent-2-ynyl ester 

Relevant articles and documents

Azocinoindole synthesis by a gold(I)-catalyzed ring expansion of 2-propargyl-β-tetrahydrocarboline

A new methodology taking advantage of gold(I)-catalyzed ring expansion has been developed to assemble tricyclic 1H-azocino[5,4-b]indoles from 2-propargyl-β-tetrahydrocarbolines. The azocinoindoles were obtained in moderate to excellent yields; the structure of which was established by X-ray crystallographic analysis. A mechanism involving regioselective intramolecular hydroarylation, [1,2]-alkenyl migration and carbon-carbon bond-fragmentation was proposed. Route to ring expansion: A new methodology taking advantage of gold(I)-catalyzed ring expansion has been developed to assemble tricyclic 1H-azocino[5,4-b]indoles from 2-propargyl-β-tetrahydrocarbolines (see scheme; EWG= electron-withdrawing group). A mechanism involving regioselective hydroarylation, [1,2]-alkenyl migration, and carbon-carbon bond fragmentation was proposed.