1613250-69-3Relevant academic research and scientific papers
Dual roles of sulfonyl hydrazides: A three-component reaction to construct fully substituted pyrazoles using TBAI/TBHP
Zhang, Jie,Shao, Ying,Wang, Hongxiang,Luo, Qiang,Chen, Jijun,Xu, Dongmei,Wan, Xiaobing
supporting information, p. 3312 - 3315 (2014/07/08)
A mild and rapid approach has been developed for the construction of fully substituted pyrazoles using TBAI as a catalyst and TBHP as an oxidant, in which tosylhydrazide functions as the ring component and sulfonyl precursor. This protocol features a wide substrate scope with a broad range of functional group tolerance, utilizes easily available starting materials, can be scaled-up, and is operationally simple.
