1613308-86-3

Upstream product

• 1075-77-0 (E)-4-chlorocinnamic aldehyde 
• 39081-26-0 2-(1-Methyl-2-oxo-1,2-dihydro-indol-3-ylidene)-malononitrile 
• 1613309-12-8 E-1-(4-Chlorophenyl)penta-1,4-dien-3-one 

Relevant academic research and scientific papers

Phosphine-catalyzed asymmetric formal [4+2] tandem cyclization of activated dienes with isatylidenemalononitriles: Enantioselective synthesis of multistereogenic spirocyclic oxindoles

The first highly enantioselective formal [4+2] tandem cyclizations between isatylidenemalononitriles and activated dienes catalyzed by bifunctional chiral phosphine catalysts have been developed, yielding multistereogenic spirocyclic oxindoles in high yie