1613458-53-9Relevant academic research and scientific papers
Rhenium-catalyzed α-alkylation of enol acetates with alcohols or ethers
Umeda, Rui,Takahashi, Yuuki,Yamamoto, Takaaki,Iseki, Hideki,Osaka, Issey,Nishiyama, Yutaka
supporting information, p. 92 - 101 (2018/11/01)
When benzylic and allylic alcohols were treated with enol acetate in the presence of a catalytic amount of a rhenium complex, ReBr(CO)5, the carbon-carbon bond formation of the alcohols and enol acetate smoothly proceeded to give the corresponding ketones and aldehyde in moderate to good yields. For the reaction of allylic alcohols, γ,δ-unsaturated carbonyl compounds were obtained in good yields. When ethers were used instead of alcohols as the alkylated agent, two alkyl moieties on the ethers were utilized on the reaction.
Triflic acid promoted direct α-alkylation of unactivated ketones using benzylic alcohols via in situ formed acetals
Koppolu, Srinivasa Rao,Naveen, Naganaboina,Balamurugan, Rengarajan
supporting information, p. 6069 - 6078 (2014/07/21)
Direct α-alkylation of unactivated ketones using benzylic alcohols as electrophiles has been achieved at room temperature. This reaction takes place via in situ formed acetal using triflic acid and trimethyl orthoformate. It is believed that methyl vinyl
