1613546-27-2

Upstream product

• 1613546-25-0 methyl 5,5,5-trifluoro-4-((4-methoxyphenyl)imino)pent-2-ynoate 
• 1613546-26-1 methyl 6-(4-chlorophenyl)-5-fluoro-4-((4-methoxyphenyl)amino)picolinate 
• 104-94-9 4-methoxy-aniline 
• 75999-66-5 N-(4-methoxyphenyl)trifluoroacetimidoyl chloride 

Downstream Products

• 496850-12-5 methyl 4-amino-3-chloro-6-(4-chlorophenyl)-5-fluoropicolinate 
• 496851-93-5 4-amino-3-chloro-6-(4-chlorophenyl)-5-fluoropicolinic acid 
• 1390640-88-6 methyl 4-amino-6-(4-chlorophenyl)-5-fluoropicolinate 

Relevant academic research and scientific papers

Synthesis of Novel Fluoropicolinate Herbicides by Cascade Cyclization of Fluoroalkyl Alkynylimines

The cascade cyclization of fluoroalkyl alkynylimines with primary amines has been modified to allow the synthesis of 4-amino-5-fluoropicolinates. Use of N-trityl and acetal protecting groups in the cyclization precursor led to 5-fluoropyridines that were

PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-CHLORO-6-(SUBSTITUTED)PICOLINATES

4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a C1-C4 alkyl propiolate and a substituted methylene amine by a series of steps.