161359-33-7Relevant academic research and scientific papers
Synthesis of 5-amino-4-sulfonamidoimidazole nucleosides as potential inhibitors of purine nucleotide biosynthesis, and of an imidazothiadiazine dioxide analogue of adenosine
Frame, A. Scott,Wightman, Richard H.,Mackenzie, Grahame
, p. 9219 - 9236 (2007/10/03)
5-Amino-4-sulfonamido-1-(β-D-ribofuranosyl)imidazole 6 and two more complex sulfonamides, one of which (8) incorporates an L-aspartyl unit, have been prepared as potential inhibitors of the intermediate stages in the pathway for de novo biosynthesis of pu
The synthesis of novel transition state analogues related to imidazole and purine nucleotides involved in the de novo biosynthesis of purines
Frame,Wightman,Mackenzie
, p. 363 - 366 (2007/10/02)
5-Amino-4-sulphonamidoimidazole ribofuranosyl nucleosides and a related imidazothiadiazine dioxide nucleoside have been synthesized as potential inhibitors of enzymes involved in the de novo biosynthesis of purine nucleotides.
