1613624-76-2

Upstream product

• 1417189-24-2 C₂₈H₃₄N₂O₆ 
• 1613624-75-1 (S)-4-(4-(4-(benzyloxycarbonylamino)but-1-ynyl)phenyl)-2-(tert-butoxycarbonylamino)butanoic amide 
• 1613624-74-0 (S)-4-(4-(4-(benzyloxycarbonylamino)but-1-ynyl)phenyl)-2-(tert-butoxycarbonylamino)butanoic acid 

Downstream Products

• 1613624-77-3 C₂₂H₂₉N₃O₃*ClH 
• 1613624-78-4 C₃₀H₄₄N₄O₅ 
• 1613624-79-5 C₃₈H₅₀N₄O₇ 
• 1613624-80-8 C₃₃H₄₂N₄O₅ 

Relevant academic research and scientific papers

3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS

The present invention relates compounds of the formula: or pharmaceutically acceptable salts thereof, useful as sodium channel blockers, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including cystic fibrosis, chronic obstructive pulmonary disease, asthma, bronchiectasis, acute and chronic bronchitis, emphysema, and pneumonia.

3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS

The present invention relates compounds of the formula: or pharmaceutically acceptable salts thereof, useful as sodium channel blockers, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including cystic fibrosis, chronic obstructive pulmonary disease, asthma, bronchiectasis, acute and chronic bronchitis, emphysema, and pneumonia.