1613703-72-2Relevant academic research and scientific papers
Total synthesis of the indole alkaloids henrycinol A and B
Prasad, Kavirayani R.,Nidhiry, John Eugene,Sridharan, Makuteswaran
, p. 4611 - 4616 (2014)
The total synthesis of new indole alkaloids henrycinol A and B were accomplished starting from l-tryptophan methyl ester. The key step is a stereochemically flexible Pictet-Spengler reaction governed by the presence or absence of an N-allyl group in the tryptophan precursor. The natural products henrycinol A and B were synthesized in good overall yield in eight and nine steps, respectively.
