161374-07-8

Basic information

• Product Name: ETHYL 4-(4-METHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE
• Synonyms: SALOR-INT L481009-1EA;BUTTPARK 42\07-46;AURORA 1141;ETHYL 4-(4-METHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE;ethyl 4-(4-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
• CAS NO: 161374-07-8
• Molecular Formula: C₁₅H₁₈N₂O₄
• Molecular Weight: 290.31
• Mol File: 161374-07-8.mol
• Article Data: 125

Chemical Properties

• Melting Point: 201-202 °C
• Boiling Point: 422.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.177±0.06 g/cm3(Predicted)
• PKA: 11.40±0.70(Predicted)
• CAS DataBase Reference: ETHYL 4-(4-METHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-(4-METHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE(161374-07-8)
• EPA Substance Registry System: ETHYL 4-(4-METHOXYPHENYL)-6-METHYL-2-OXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE(161374-07-8)

Safety Data

• Hazardous Substances Data: 161374-07-8(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 123-11-5 4-methoxy-benzaldehyde 
• 57-13-6 urea 
• 105-13-5 4-Methoxybenzyl alcohol 
• 52772-80-2 1,1'-[(4-methoxyphenyl)methylene]diurea 
• 119-52-8 4,4'-dimethoxybenzoin 
• 4464-76-0 1,2-bis(4-methoxyphenyl)-1,2-ethanediol 
• 6292-71-3 4-methoxybenzaldehyde semicarbazone 
• 17356-08-0 thiourea 
• 4433-85-6 2-ethyl-3-oxobutanoic acid 
• 913696-92-1 4-(4-methoxyphenyl)-6-methyl-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid ethyl ester 
• 867372-86-9 phenyl [(p-metoxyphenyl)(tosyl)methyl]carbamate 
• 867372-91-6 2-[(4-methoxy-phenyl)-phenoxycarbonylamino-methyl]-3-oxo-butyric acid ethyl ester 
• 33402-67-4 sodium hydroxy(4-methoxyphenyl)methanesulfonate 

Downstream Products

• 847259-60-3 4-anisyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-5-carbohydrazide 
• 302821-59-6 C₁₇H₂₀N₂O₅ 
• 5953-85-5 p-anisaldehyde hydrazone 
• 17356-08-0 thiourea 
• 57-13-6 urea 
• 132712-71-1 5-hydroxy-3-methylpyrazole 
• 1311274-15-3 C₂₅H₂₂N₈O₆ 
• 1311274-14-2 C₂₆H₂₅N₇O₅ 
• 1311274-13-1 C₂₅H₂₂ClN₇O₄ 
• 1311274-12-0 N'-(5-cyano-1-methyl-6-oxo-4-phenylpyrimidin-2-yl)-4-(4-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carbohydrazide 
• 1245716-48-6 ethyl 4-(4-methoxyphenyl)-6-methyl-2-(tosyloxy)pyrimidine-5-carboxylate 

Relevant articles and documents

Cu(ClO4)2.6H2O as an efficient catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions

Cu(ClO4)6H2O efficiently catalyzes the three-component Biginelli reaction of aldehyde,-dicarbonyl compounds, and urea or thiourea under solvent-free conditions to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones in excellent

Ionic liquids catalyzed Biginelli reaction under solvent-free conditions

3,4-Dihydropyrimidin-2(1H)-ones were synthesised in high yields by one-pot three-component Biginelli condensation in the presence of room temperature ionic liquids such as 1-n-butyl-3-methylimidazolium tetrafluoroborate (BMImBF4) or hexafluorop

Deep eutectic solvent assisted synthesis of dihydropyrimidinones/thionesviaBiginelli reaction: theoretical investigations on their electronic and global reactivity descriptors

Deep eutectic solvents formed from hydrated metal chlorides and hydrogen bond donors (Type 4) were prepared and their catalytic activity was compared for the synthesis of dihydropyrimidinones/thionesviaBiginelli reaction at room temperature. The one-pot m

Synthesis method of dihydropyrimidinone compound

The invention discloses a synthesis method of a dihydropyrimidone compound, which belongs to the technical field of organic synthesis, and comprises the following steps: by taking benzaldehyde or a derivative thereof, ethyl acetoacetate or acetylacetone a