161389-26-0Relevant academic research and scientific papers
Inhibitors of HIV-1 proteinase containing 2-heterosubstituted 4-amino-3- hydroxy-5-phenylpentanoic acid: Synthesis, enzyme inhibition, and antiviral activity
Scholz,Billich,Charpiot,Ettmayer,Lehr,Rosenwirth,Schreiner,Gstach
, p. 3079 - 3089 (2007/10/02)
A convenient procedure for the synthesis of 2-heterosubstituted statine derivatives as novel building blocks in HIV-protease inhibitors has been developed. The synthesis starts with protected L-phenylalaninols, which were converted to γ-amino α,β-unsatura
