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Usage

Uses

Used in Pharmaceutical Industry:
(3αR,7αR)-1,3-Dimethyl-2-(1-piperidinyl)octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide is used as a potential candidate for pharmaceutical applications due to its unique structure and the diverse reactivity of phosphorus-containing compounds. Its specific application reason within the pharmaceutical industry may include its potential use in the development of new drugs or as an intermediate in the synthesis of pharmaceutical compounds.
Used in Chemical Synthesis:
In the chemical synthesis industry, (3αR,7αR)-1,3-Dimethyl-2-(1-piperidinyl)octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide may be utilized as a building block or intermediate in the synthesis of more complex molecules. Its unique structure and the presence of a phosphorus atom could provide novel reactivity and properties that are valuable in the development of new chemical products or materials.

Upstream product

• 1498-56-2 piperidin-1-yl-phosphonic acid dichloride 
• 68737-65-5 (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane 

Relevant academic research and scientific papers

Chiral phosphoramide-catalyzed enantioselective addition of allylic trichlorosilanes to aldehydes. Preparative and mechanistic studies with monodentate phosphorus-based amides

The addition of allylic trichlorosilanes to benzaldehyde promoted by chiral phosphoramides to give the enantioenriched homoallylic alcohol has been investigated. In a survey of Lewis bases as activators for the addition of allyltrichlorosilane to benzalde

Synthesis of phosphoramides for the lewis base-catalyzed allylation and aldol addition reactions

Both chiral and achiral phosphoramides of diverse structure were prepared from diamines by the coupling to phosphorus(V) or phosphorus(III) reagents. Several enantiopure 1,2-diphenyl-1,2-ethanediamine analogues have been prepared by the reductive coupling of the corresponding N-silylimine with NbCl4(THF)2 and subsequent resolution by the formation of diastereomeric menthyl carbamates. (S,S)-N,N'-Di-(1-naphthyl)-1,2-diphenyl- 1,2-ethanediamine 15 was prepared by the arylation of (S,S)-1,2-diphenyl- 1,2-ethanediamine with naphthyl iodide.