1614-11-5

Basic information

• Product Name: 2-AMINOBENZOTRIAZOLE
• Synonyms: 2-AMINOBENZOTRIAZOLE;2-BENZOTRIAZOLAMINE;2H-1,2,3-BENZOTRIAZOL-2-AMINE;2-Amino-2H-benzotriazole
• CAS NO: 1614-11-5
• Molecular Formula: C6H6N4
• Molecular Weight: 134.14
• Mol File: 1614-11-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 122 °C
• Boiling Point: 319.3°Cat760mmHg
• Flash Point: 146.9°C
• Appearance: /
• Density: 1.5g/cm³
• Vapor Pressure: 0.000341mmHg at 25°C
• Refractive Index: 1.773
• Solubility: soluble in Methanol
• PKA: 4.02±0.30(Predicted)
• CAS DataBase Reference: 2-AMINOBENZOTRIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOBENZOTRIAZOLE(1614-11-5)
• EPA Substance Registry System: 2-AMINOBENZOTRIAZOLE(1614-11-5)

Safety Data

• Hazardous Substances Data: 1614-11-5(Hazardous Substances Data)

Usage

General Description

2-aminobenzotriazole, also known as ABT, is a potent mechanism based cytochrome P450 inhibitor. It is a synthetic aromatic compound in off-white crystallized powder form. It is primarily used for research purposes, particularly for inactivation of hepatic P450 enzymes in animals undergoing pharmacotherapeutic treatment, to reduce the metabolic clearance of drugs and thereby increase the bioavailability. It is also used to study the effects of other xenobiotics. It must be handled with caution due to its potential to cause skin and respiratory irritation and long-term damage. It is considered harmful when swallowed, inhaled, or comes in contact with skin.

InChI:InChI=1/C6H6N4/c7-10-8-5-3-1-2-4-6(5)9-10/h1-4H,7H2