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2-Aminobenzotriazole (ABT) is a potent mechanism-based cytochrome P450 inhibitor, a synthetic aromatic compound that appears as an off-white crystallized powder. It is primarily utilized for research purposes, focusing on the inactivation of hepatic P450 enzymes in animals receiving pharmacotherapeutic treatment. This inactivation helps to reduce the metabolic clearance of drugs, thereby increasing their bioavailability. Additionally, ABT is employed in studies examining the effects of other xenobiotics. Due to its potential to cause skin and respiratory irritation, as well as long-term damage, it must be handled with caution. It is classified as harmful when swallowed, inhaled, or comes in contact with the skin.

1614-11-5

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1614-11-5 Usage

Uses

Used in Pharmaceutical Research:
2-Aminobenzotriazole is used as a cytochrome P450 inhibitor for the purpose of inactivating hepatic P450 enzymes in animals undergoing pharmacotherapeutic treatment. This application helps to reduce the metabolic clearance of drugs, thereby increasing their bioavailability and allowing for more effective treatment.
Used in Xenobiotic Studies:
2-Aminobenzotriazole is used as a research tool to study the effects of other xenobiotics on the body. Its role in these studies is to provide insights into how different substances interact with and are processed by the body's metabolic pathways, contributing to a better understanding of their potential impacts and uses.
Used in Toxicological Research:
2-Aminobenzotriazole is used as a compound of interest in toxicological research to investigate its potential harmful effects when swallowed, inhaled, or comes in contact with the skin. This research is crucial for understanding the safety profile of ABT and informing proper handling and disposal procedures to minimize health risks.

Check Digit Verification of cas no

The CAS Registry Mumber 1614-11-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,1 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1614-11:
(6*1)+(5*6)+(4*1)+(3*4)+(2*1)+(1*1)=55
55 % 10 = 5
So 1614-11-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N4/c7-10-8-5-3-1-2-4-6(5)9-10/h1-4H,7H2

1614-11-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Aminobenzotriazole

1.2 Other means of identification

Product number -
Other names benzotriazol-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1614-11-5 SDS

1614-11-5Upstream product

1614-11-5Downstream Products

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