161406-19-5

Basic information

• Product Name: 4-AMinobenzoic Acid-13C6
• Synonyms: 4-AMinobenzoic Acid-13C6;Actipol-13C6;AMben-13C6;Bacterial VitaMin H1-13C6;PABA-13C6;Pabacyd-13C6;PabafilM-13C6;p-AMinobenzoic Acid-13C6
• CAS NO: 161406-19-5
• Molecular Formula: C₇H₇NO₂
• Molecular Weight: 137.13598
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
• Mol File: 161406-19-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-AMinobenzoic Acid-13C6(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMinobenzoic Acid-13C6(161406-19-5)
• EPA Substance Registry System: 4-AMinobenzoic Acid-13C6(161406-19-5)

Safety Data

• Hazardous Substances Data: 161406-19-5(Hazardous Substances Data)

Usage

Uses

Labelled p-Aminobenzoic Acid. Widely distributed in nature as a B complex factor. Baker’s yeast contains 5 to 6 ppm, brewer’s yeast from 10 to 100 ppm. Occurs free and in ester form.

Upstream product

• 233600-81-2 <1,2,3,4,5,6-(13)C6>-p-iodotrifluoroacetanilide 
• 233600-82-3 <1,2,3,4,5,6-(13)C6>-p-trifluoroacetamidobenzoic acid 

Downstream Products

• 233600-85-6 <1',2',3',4',5',6'-(13)C6>-N(2)-acetyl-N(10)-trifluoroacetylpteroic acid 
• 233600-84-5 <1',2',3',4',5',6'-(13)C6>-N(2)-acetylpteroic acid 

Relevant articles and documents

The synthesis of folic acid, multiply labelled with stable isotopes, for bio-availability studies in human nutrition

Two different methods for the synthesis of folic acid, which are suitable for the incorporation of compounds multiply labelled with stable isotopes, are described. The first method is based on the use of a novel reductive amination to link 2-acetyIamino-4-hydroxy-6-formylpteridine withp-aminobenzoyl-L-glutamic acid. The second method is based on the penultimate formation of an amide bond between Ar-2-acetyl-Ar-10-trifluoroacetyIpteroic acid and dimethyl L-glutamate. Both methods have been used to transform [13C6]aniline into folic acid, labelled with [13C6] in the p-aminobenzoate moiety, and [3,3,4,4-2H4]-L-glutamic acid into folic acid, labelled with [2H4] in the glutamate moiety. Doubly labelled [13C6,2H 4]-p-aminobenzoyl-L-glutamate has also been prepared by the former method.