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161417-20-5

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161417-20-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 161417-20-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,4,1 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 161417-20:
(8*1)+(7*6)+(6*1)+(5*4)+(4*1)+(3*7)+(2*2)+(1*0)=105
105 % 10 = 5
So 161417-20-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H16N2O/c1-9-11(5-3-6-12-9)14-8-10-4-2-7-13-10/h3,5-6,10,13H,2,4,7-8H2,1H3

161417-20-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methyl-3-(2-pyrrolidinylmethoxy)pyridine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:161417-20-5 SDS

161417-20-5Downstream Products

161417-20-5Relevant articles and documents

3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release

-

, (2008/06/13)

Novel heterocyclic ether compounds of the formula: STR1 wherein n, *, R1, R2, R3 and y are specifically defined, or pharmaceutically acceptable salts or prodrugs thereof, which are useful in selectively controlling neurotransmitter release; therapeutically-effective pharmaceutical compositions of these compounds; and use of said compositions to selectively control neurotransmitter release in mammals.

Structure-activity studies on 2-methyl-3-(2(S)- pyrrolidinylmethoxy)pyridine (ABT-089): An orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties

Lin, Nan-Horng,Gunn, David E.,Ryther, Keith B.,Garvey, David S.,Donnelly-Roberts, Diana L.,Decker, Michael W.,Brioni, Jorge D.,Buckley, Michael J.,Rodrigues, A. David,Marsh, Kennan G.,Anderson, David J.,Buccafusco, Jerry J.,Prendergast, Mark A.,Sullivan, James P.,Williams, Michael,Arneric, Stephen P.,Holladay, Mark W.

, p. 385 - 390 (2007/10/03)

2-Methyl-3-(2(S)-pyrrolidinylmethoxy)pyridine, ABT-089 (S-4), a member of the 3-pyridyl ether class of nicotinic acetylcholine receptor (nAChR) ligands, shows positive effects in rodent and primate models of cognitive enhancement and a rodent model of anxiolytic activity and possesses a reduced propensity to activate peripheral ganglionic type receptors. The profiles of S-4, its N-methyl analogue, and the corresponding enantiomers across several measures of cholinergic channel function in vitro and in vivo are presented, together with in vitro metabolism and in vivo bioavailability data. On the basis of its biological activities and favorable oral bioavailability, S-4 is an attractive candidate for further evaluation as a treatment for cognitive disorders.

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