16144-91-5Relevant articles and documents
Cookson,Hill
, p. 2023,2026 (1963)
Singlet Oxygenation of a Conjugated Diallene: Attempt to Prepare a Stable Divinyl Peroxide
Mebane, Robert C.,Schuster, Gary B.
, p. 810 - 812 (1983)
A conjugated diallene, 2,3-divinylidenebicycloheptane, was prepared and isolated.Photosensitized oxygenation of this allene leads to two isolated oxygenated products in 50percent yield.Detection of these products is interpreted to implicate an unstable cyclic divinyl peroxide intermediate.Attempts to detect this intermediate by low temperature NMR spectroscopy and by chemiluminescence were unsuccessful.The instability of this compound is attributed to the destabilizing lone-pair interaction of the peroxide oxygen atoms.
BRIDGED RING COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
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Paragraph 0218; 0258; 0259, (2017/04/11)
Provided herein is a bridged bring compound of formula (I) or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, which can be used for treating treat hepatitis C virus (HCV) infection or hepatitis C disease. Furthermore provided herein are pharmaceutical compositions containing the compounds and the method of using the compounds or pharmaceutical compositions thereof in the treatment of HCV infection or hepatitis C.
BRIDGED RING COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
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, (2015/08/06)
Provided herein is a bridged bring compound of formula (I) or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, which can be used for treating treat hepatitis C virus (HCV) infection or hepatitis C disease. Furthermore provided herein are pharmaceutical compositions containing the compounds and the method of using the compounds or harmaceutical com ositions thereof in the treatment of HCV infection or he atitis C.