161446-26-0

Basic information

• Product Name: (E)-7-[(1R,2S,3R)-3-Hydroxy-2-((R)-3-hydroxy-4-phenoxy-but-1-ynyl)-5-oxo-cyclopentyl]-hept-2-enoic acid methyl ester
• CAS NO: 161446-26-0
• Molecular Weight: 400.472
• Mol File: 161446-26-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-7-[(1R,2S,3R)-3-Hydroxy-2-((R)-3-hydroxy-4-phenoxy-but-1-ynyl)-5-oxo-cyclopentyl]-hept-2-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-7-[(1R,2S,3R)-3-Hydroxy-2-((R)-3-hydroxy-4-phenoxy-but-1-ynyl)-5-oxo-cyclopentyl]-hept-2-enoic acid methyl ester(161446-26-0)
• EPA Substance Registry System: (E)-7-[(1R,2S,3R)-3-Hydroxy-2-((R)-3-hydroxy-4-phenoxy-but-1-ynyl)-5-oxo-cyclopentyl]-hept-2-enoic acid methyl ester(161446-26-0)

Safety Data

• Hazardous Substances Data: 161446-26-0(Hazardous Substances Data)

Upstream product

• 149862-37-3 (R)-3-<(tert-butyldimethylsilyl)oxy>-4-phenoxy-1-butyne 
• 117254-07-6 (4R)-2-(N,N-diethylamino)methyl-4-(t-butyldimethylsiloxy)-cyclopent-2-en-1-ol 
• 77823-74-6 (E)-6-Iod-2-hexensaeure-methylester 
• 161446-38-4 (E)-7-{(1R,2S,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(R)-3-(tert-butyl-dimethyl-silanyloxy)-4-phenoxy-but-1-ynyl]-5-oxo-cyclopentyl}-hept-2-enoic acid methyl ester 

Relevant articles and documents

Synthesis and structure-activity relationships of a new class of selective EP3 receptor agonist, 13,14-didehydro-16-phenoxy analogues of prostaglandin E1

A series of 13,14-didehydro-16-phenoxy analogues of prostaglandin E1 was synthesized and their agonistic activity on EP receptor subtypes was evaluated. 13,14-Didehydro-16-phenoxy-1-decarboxy analogues, 7e and 7f, display highly selective activity on the EP3 receptor subtype, thus, their utility as a selective anti-ulcer agent can be expected. (C) 2000 Elsevier Science Ltd.