16148-15-5

Basic information

• Product Name: (R)-(+)-1-(4-fluorophenyl)-1-propanol
• CAS NO: 16148-15-5
• Molecular Formula: C₉H₁₁FO
• Molecular Weight: 154.1814432
• Mol File: 16148-15-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-(+)-1-(4-fluorophenyl)-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-1-(4-fluorophenyl)-1-propanol(16148-15-5)
• EPA Substance Registry System: (R)-(+)-1-(4-fluorophenyl)-1-propanol(16148-15-5)

Safety Data

• Hazardous Substances Data: 16148-15-5(Hazardous Substances Data)

Upstream product

• 557-20-0 diethylzinc 
• 459-57-4 4-fluorobenzaldehyde 

Relevant articles and documents

A new chiral sulfonamide ligand based on tartaric acid: synthesis and application in the enantioselective addition of diethylzinc to aldehydes and ketones

A new sulfonamide ligand based on l-tartaric acid was synthesized and was employed as a chiral ligand in the enantioselective addition of diethylzinc to aldehydes, giving rise to the best enantiomeric excess up to 83% with 5 mol % of catalyst loading. Moreover, the addition of diethylzinc to ketones can also be achieved with good to excellent enantioselectivities by employing 7 mol % of the catalyst under mild conditions.

Asymmetric synthesis of optically active fluorine-containing alcohols using chiral catalysts

Optically active fluorine-containing alcohols have been synthesized in high enantiomeric excess by the catalytic enantioselective addition of dialkylzincs to fluorine-containing aldehydes.