16148-15-5Relevant articles and documents
A new chiral sulfonamide ligand based on tartaric acid: synthesis and application in the enantioselective addition of diethylzinc to aldehydes and ketones
Hui, Ailing,Zhang, Jintang,Fan, Jinmin,Wang, Zhiyong
, p. 2101 - 2107 (2007/10/03)
A new sulfonamide ligand based on l-tartaric acid was synthesized and was employed as a chiral ligand in the enantioselective addition of diethylzinc to aldehydes, giving rise to the best enantiomeric excess up to 83% with 5 mol % of catalyst loading. Moreover, the addition of diethylzinc to ketones can also be achieved with good to excellent enantioselectivities by employing 7 mol % of the catalyst under mild conditions.
Asymmetric synthesis of optically active fluorine-containing alcohols using chiral catalysts
Soai, Kenso,Hirose, Yuji,Niwa, Seiji
, p. 5 - 8 (2007/10/02)
Optically active fluorine-containing alcohols have been synthesized in high enantiomeric excess by the catalytic enantioselective addition of dialkylzincs to fluorine-containing aldehydes.