161511-14-4

Basic information

• Product Name: trans-3,trans-4-bis(benzyloxymethyl)-1,2-epoxycyclobutane
• Synonyms: trans-3,trans-4-bis(benzyloxymethyl)-1,2-epoxycyclobutane
• CAS NO: 161511-14-4
• Molecular Weight: 310.393
• Mol File: 161511-14-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: trans-3,trans-4-bis(benzyloxymethyl)-1,2-epoxycyclobutane(CAS DataBase Reference)
• NIST Chemistry Reference: trans-3,trans-4-bis(benzyloxymethyl)-1,2-epoxycyclobutane(161511-14-4)
• EPA Substance Registry System: trans-3,trans-4-bis(benzyloxymethyl)-1,2-epoxycyclobutane(161511-14-4)

Safety Data

• Hazardous Substances Data: 161511-14-4(Hazardous Substances Data)

Upstream product

• 77774-01-7 (1R,4S)-(4-hydroxymethylcyclobut-2-enyl)methanol 
• 161395-11-5 cis-3,4-bis(benzyloxymethyl)cyclobut-1-ene 

Downstream Products

• 172688-27-6 (1S,2R,3S)-2,3-Bis-benzyloxymethyl-cyclopropanecarbaldehyde 
• 172822-65-0 1-((1R,2S,3R)-2,3-Bis-benzyloxymethyl-cyclopropylmethyl)-5-methyl-1H-pyrimidine-2,4-dione 
• 945230-94-4 Methanesulfonic acid (1S,2R,3S)-2,3-bis-benzyloxymethyl-cyclopropylmethyl ester 
• 172822-63-8 ((1R,2S,3R)-2,3-Bis-benzyloxymethyl-cyclopropyl)-methanol 

Relevant articles and documents

Novel Cyclobutane Carbocyclic Nucleosides

Epoxidation of cis-3,4-bis(benzyloxymethyl)cyclobut-1-ene 4 gave compounds 7a and 7b which were separated.Reaction of the cis-epoxide 7a with adenine led to the N-9 and N-7 attack products, 10a and 10b, respectively.In the same conditions, the trans-epoxi

Preparation Involving a C4-C3 Ring Contraction in the Key Step of a Novel Cyclopropane Carbocyclic Nucleoside

Cis-3,4-bis(benzyloxymethyl)cyclobut-1-ene 1 mainly led to bromohydrin 5 with a cis relationship between bromine and the benzyloxymethyl groups.The stereospecific ring contraction of 5 afforded aldehyde 7 which could be converted into the nucleoside analo