16154-72-6 Usage
General Description
3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE is a chemical compound that consists of a chloro-substituted aniline ring with a piperazine ring attached. It is commonly used in the synthesis of pharmaceuticals and research chemicals. 3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE has the potential to act as a pharmaceutical intermediate in the production of various drugs, including antipsychotics and antidepressants. Additionally, it may also be used in the development of other organic compounds for research purposes. The presence of a chloro group and piperazine ring in its structure allows for potential interactions with biological systems, making it an important compound in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 16154-72-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,5 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16154-72:
(7*1)+(6*6)+(5*1)+(4*5)+(3*4)+(2*7)+(1*2)=96
96 % 10 = 6
So 16154-72-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H16ClN3/c1-14-4-6-15(7-5-14)11-3-2-9(13)8-10(11)12/h2-3,8H,4-7,13H2,1H3
16154-72-6Relevant articles and documents
PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER
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, (2021/04/23)
The invention provides compounds of the formula (1): or a salt or tautomer thereof wherein A, R1, R2, R3, R4, R5 and R6 are as defined herein. The compounds are inhibitors of Wee1 and/or PLK1 kinase and are envisaged to be useful in the treatment of cancers.
WEE1 inhibitors as well as preparation and application thereof
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, (2020/10/14)
The invention relates to WEE1 inhibitors as well as preparation and application thereof. The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, solvates, polymorphs or isomers thereof, and their use in the preparation of medicaments for the treatment of diseases associated with WEE1 activity.
POTENT DUAL BRD4-KINASE INHIBITORS AS CANCER THERAPEUTICS
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, (2016/04/26)
Disclosed herein are compounds that are inhibitors of BRD4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BRD4 are also disclosed. In certain aspects, disclosed are compounds of Formula I-IV.