1615702-57-2Relevant academic research and scientific papers
Palladium-nanoparticle-catalyzed 1,7-palladium migration involving C-H activation, followed by intramolecular amination: Regioselective synthesis of N 1-arylbenzotriazoles and an evaluation of their inhibitory activity toward indoleamine 2,3-dioxygenase
Takagi, Koji,Al-Amin, Mohammad,Hoshiya, Naoyuki,Wouters, Johan,Sugimoto, Hiroshi,Shiro, Yoshitsugu,Fukuda, Hayato,Shuto, Satoshi,Arisawa, Mitsuhiro
, p. 6366 - 6371 (2014)
A sulfur-modified gold-supported palladium material (SAPd) has been developed bearing palladium nanoparticles on its surface. Herein, we report for the first time the use of SAPd to affect a Pd-nanoparticle-catalyzed 1,7-Pd migration reaction for the synthesis of benzotriazoles via C-H bond activation. The resulting benzotriazoles were evaluated in terms of their inhibitory activity toward indoleamine 2,3-dioxygenase.
